It took me around 25 hours, which surprised me in both how many hours i put in and how much there was still left to do, if i wanted. I dont think ive sank this amount of time into a game in a while. I was only level 19 before i decided to finish up as Mr. Houses lackey. For this first play through, i let me myself choose what i thought would be right and i honestly think House has the best vision for New Vegas. The legion seems crazy and the NCR a bunch of military bullies... I was tempted to do the route that put vegas under my control, but i believed in Mr. House, haha. My character had his energy weapons up to 100 while speech and science were 80 (i used magezines for the extra 20 if needed. 20 because of some perk i picked that would give me double magezine bonuses). Lockpick was pretty high, too.
All in all i liked my build and the ending to the route i chose. Although, i was never able to find really cool energy weapons... I never found a sniper equivalent and i bought a bunch of laser gatling mods, but never ended up finding the laser gatling... In the end i was using a heavy incinerator and a laser rifle with scope and +damage mods. Even still, things are frigging tough to kill in this game. If not for companions and/or the securibots at the end, i wouldnt have been able to do crap.
I did make appropriate saves so that i can load up and choose a different ending path, but i think instead i'll make a melee or explosives character and start from the beginning. This, again, will be the first game i'll replay in a long time, too! Good stuff.