I use the Mayday tileset, and play in worlds with no aquifers, just because they limit progress too much without using irritating methods to mine through that layer. The therapist app as well.
I have attempted the isometric view mods, but I find that they seem to only be good as a display for other people to watch the game on rather than actually try to play using it.
Although getting into the game is not nearly as difficult as people make it out to be. The only real issue is, as this guy says, that players should follow tool tips and ignore most of the options available at the beginning of the game.
I do think this game could benefit from a tutorial or mini-quest system for new players though.
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